French researchers conducted laboratory and field experiments to determine the efficacy of Duddingtonia flagran spores. For all the trials, half of the goats received the spores while the other half acted as controls. For the dose titration trial, two dose levels were given.
In the laboratory experiment, the reduction of larval development in goat feces containing D. flagrans spores when compared with the larval development in control feces was 91% and 90%, respectively for T. colubriformis and T. circumcincta.
In the farm trial, none of the parasitological parameters (egg excretion, pasture infectivity, and serum pepsinogen ) showed any statistical difference between the fungus-treated and the control groups. The growth of kids of the two groups was the same.
In laboratory conditions, whatever the dose rate, the larval development reduction was higher than 75% when compared with a control group, and there was no difference between the doses. With trough administration, a significant increase in the larval development reduction was observed with the higher dose.
Since efficacy of the fungus has been demonstrated, the researchers hypothesized that variations in voluntary consumption (by kid goats) may explain the lack of efficacy observed in the field trial.
Source: International Society for Animal Hygiène - Saint-Malo - 2004
BioWorma® contains spores of Duddingtonia Flagrans.