Moxidectin Prevents PPER

The periparturient egg rise (PPER) is a well-documented phenomenon in small ruminants, whereby ewes and does suffer a temporary loss of immunity to parasites around the time of parturition. Researchers tested the impact of moxidectin at peripartum on fecal egg counts and clinical parameters of ewes and lambs in the high altitude tropical Andes of Colombia. Twenty-nine healthy, naturally-infected ewes of four breeds (Colombian Creole, Romney Marsh, Hampshire, and Corriedale) were given moxidectin at either day ~135 of pregnancy (T1, n=15) or 48 hours after parturition (T2, n=14). Fourteen untreated ewes served as controls (C). Suckling lambs (n=58) remained untreated, but were evaluated as p

Could Deworming Pets Fuel Resistance?

As a veterinarian working in companion animal medicine, Dr. Chiara Switzer knows that her profession widely recommends treating dogs and cats routinely with drugs to prevent infestations of heartworm and intestinal parasites. The approach is meant not only to keep the pets healthy but to minimize the risk of animals transmitting parasites to their human families — a compelling consideration, Switzer says. At the same time, she worries that this highly touted regimen might do harm in the long run. Read more

Pre-Lamb Drench Selects for Resistance

In New Zealand, it is a common practice to give a long-acting drench to pregnant ewes. Similarly, ewes (and does) in the US are often dewormed prior to parturition. But is this a good idea? Or does it select for resistant worms through the offspring? It has long been known that some drugs transfer through the ewe's milk to the lambs. In particular, Macrocylic Lactones (ML), because of their lipophilic nature, are detectable in the milk of treated animals and in the plasma of the suckling offspring. So, a study was conducted to confirm the transfer of ML actives to lambs in the ewe's milk, and to assess whether this could result in selection for ML resistant nematodes in the lamb. Long-acting

Selection for parasite resistance in goats

In fall 2011, Lincoln University (in Missouri) began a divergent selection program for parasite resistance in goats. Researchers assigned 146 mixed-age Boer and high-percentage Boer does to one of two divergent selection lines: low parasite resistance and high parasite resistance. Does were mated to unrelated Kiko bucks, selected for either high or low resistance, from buck tests in Oklahoma and Maryland. After this, lines were closed and selection was from within lines. Various genetic parameters were calculated from the population. The heritability estimate for fecal egg count (FEC) was determined to be 0.13 ± 0.07. In the scientific literature, heritability estimates for FEC for goats r

A Part of Florida History

Over the years, numerous studies have documented the parasite resistance of the "Native" sheep of the Southeast (Florida and Gulf Coast Natives), including the lack of a periparturient egg rise. These breeds represent a valuable genetic resource to the US sheep industry, as it grapples with ways to combat widespread anthelmintic resistance. The Florida Cracker is a heritage breed and one of the oldest breeds of sheep in the United States. It believed to have descended from sheep (Churro) brought to Florida during the 1500's by Spanish explorers. After being abandoned by the settlers, the sheep roamed free for centuries, gradually and naturally adapting to the hot, humid conditions of Florid

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